Which symptom is NOT a major sign suggestive of cardiovascular disease?

Frequent headaches are not considered a major sign suggestive of cardiovascular disease. In the context of cardiovascular symptoms, the focus is typically on indicators directly related to heart function and blood flow. Symptoms such as chest pain, shortness of breath, and palpitations or tachycardia are commonly associated with cardiovascular issues because they reflect the heart's ability to pump blood effectively and the overall functioning of the cardiovascular system.

Chest pain can indicate conditions like angina or myocardial infarction, while shortness of breath may suggest heart failure or other cardiopulmonary conditions. Palpitations or tachycardia can be signs of arrhythmias or other heart-related disturbances. In contrast, headaches are more general symptoms that can arise from various causes, including tension, migraines, or even stress, rather than being specific indicators of cardiovascular disease. Therefore, while they may occur in some individuals with cardiovascular issues, they are not primary symptoms linked directly to cardiovascular health.